Table 1
Mean clinical outcomes per cycle compared between laser-assisted and conventional ICSI of mature (MII) oocytes, including within-patient correlation coefficients (r).

 		Laser-assisted ICSI
 		Conventional ICSI
 		r
 		Treatment effect (95% CI)
 		P-value
Mature oocytes
 		6.6 (388)a
 		6.6 (387)a


Percent 2pn
 		71.0 (276)a
 		71.3 (278)a
 		0.39
 		-0.3 (-7.2-6.6)
 		0.94
Percent oocyte degeneration
 		11.4 (43)a
 		12.6 (44)a
 		0.33
 		-1.2 (-6.2-3.8)
 		0.63
Cell number, day 2
 		3.0
 		2.9
 		0.46
 		0.1 (-0.1-0.3)
 		0.51
Percent fragmentation, day 2
 		7.0
 		8.4
 		0.57
 		-1.4 (-3.6-0.9)
 		0.23
Cell number, day 3
 		5.7
 		5.5
 		0.48
 		0.2 (-0.2-0.5)
 		0.38
Percent fragmentation, day 3
 		9.0
 		10.6
 		0.64
 		-1.6 (-4.0-0.7)
 		0.16
Embryos/ET, day 3, n = 43
 		1.4 (60)a
 		1.2 (52)a
 		-0.46
 		0.2 (-0.2-0.6)
 		0.32
Embryos/ET, blast, n = 14
 		1.2 (17)a
 		0.7 (10)a
 		-0.74
 		0.5 (-0.2-1.2)
 		0.15
Percent compactionb
 		46.5 (121/216)a
 		54.9 (137/226)a
 		0.49
 		-8.3 (-20.2-3.6)
 		0.17
Percent blastocystb
 		28.7 (78/216)a
 		33.1 (83/226)a
 		0.28
 		-4.4 (-15.4-6.7)
 		0.43
Percent compaction, blast ET
 		90.3 (84/93)a
 		89.5 (76/85)a
 		0.32
 		0.7 (-7.2-8.7)
 		0.84
Percent blastocyst, blast ET
 		65.1 (61/93)a
 		51.7 (48/85)a
 		0.57
 		13.5 (-0.1-27.0)
 		0.051
a Numbers in parentheses are total number of oocytes or embryos.
b Compaction and blastocyst formation rates based on all embryos that were not transferred on day 3.