Authors
|
Year
|
Main findings
|
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Johnson et al.
|
2004
|
Germline stem cells are located within the ovarian epithelium and supply the adult mouse ovary with new oocytes.
|
Johnson et al.
|
2005
|
Germline stem cells are present in the circulation and supply the adult mouse ovary with new oocytes.
|
Byskov et al.
|
2005
|
Failed to find any BrdU positive oogonia within the ovarian epithelium and provided evidence to suggest that an overestimation of atretic follicle number contributed to Johnson et al.'s conclusions.
|
Oktay et al.,
|
2005
|
Reported spontaneous pregnancy in presumably sterile patient following chemotherapy, hematopoeitic stem cell transplantation and ovarian tissue transplantation.
|
Bristol-Gould et al.
|
2006
|
Showed that follicle numbers gradually decline in the mouse ovary with age and used mathematical modeling to determine that de novo follicle production is not required to support fertility.
|
Eggan et al.
|
2006
|
Used parabiotic mice to show that ovulated oocytes do not come from circulating stem cells.
|
Kerr et al.
|
2006
|
Showed that follicle numbers remain constant in mouse ovaries from puberty to early mid-life, suggesting possible follicular renewal.
|