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Clinical applications and limitations

Abstract The publication of a report in Nature in 2004 by the Tilly group suggesting that mouse ovaries are capable of generating oocytes de novo post-natally, has sparked interest in a problem long thought to have been resolved from classical studies in a variety of mammalian species. Within a nearly two year time period, laboratories […]

Comparative analysis of follicle morphology

Abstract Abstract Background Methods Results Discussion Conclusion Competing interests Authors’ contributions Acknowledgements References Background Laboratory animals are commonly used for evaluating the physiological properties of the mammalian ovarian follicle and the enclosed oocyte. The use of different species to determine the morphological relationship between the follicle and oocyte has led to a recognizable pattern of […]

No advantage of laser-assisted over conventional intracytoplasmic

Abstract Abstract Background Methods Results Discussion Conclusion Competing interests Authors’ contributions Acknowledgements References Background Intracytoplasmic sperm injection (ICSI) is a component of infertility treatment often employed when conventional in vitro fertilization is unlikely to be successful. Despite good clinical results with ICSI, the procedure is typically associated with degeneration of a significant percentage (approximately 10%) […]

In memoriam

Abstract Abstract Introduction Background Early years Further studies and research The Worcester Program and Massachusetts General Hospital years Garcia the peerless surgeon Final years and retirement Epilogue Competing interests Authors’ contributions References This article traces the career of Celso-Ramon Garcia (1922–2004), noted physician, educator, and internationally renowned pioneer in the field of reproductive endocrinology. His […]

Correlation of sperm penetration

Abstract Abstract Findings Authors’ Contributions References Background The sperm penetration assay (SPA) is used to predict the fertilizing capacity of sperm. Thus, some programs rely on SPA scores to formulate insemination plans in conjunction with in-vitro fertilization (IVF) cycles. The purpose of this study was to evaluate if a relationship exists between SPA scores and […]

Impact of seasonal variation

Background To investigate the relationship of human semen parameters with season, age and smoking status. Methods The present study used data from subjects recruited into an ongoing cross-sectional study on the relationship between environmental agents and semen characteristics. Our population consisted of 306 patients who presented to the Vincent Memorial Andrology Laboratory of Massachusetts General […]

Article processing charges

Abstract Abstract Introduction Conclusion Abbreviations Competing interests References Journal of Experimental & Clinical Assisted Reproduction is an Open Access, online, electronic journal published by BioMed Central with full contents available to the scientific and medical community free of charge to all readers. Authors maintain the copyright to their own work, a policy facilitating dissemination of […]